A new paper describing how the cytoskeletal protein vimentin can alter autophagosome and lysosome positioning, thus modulating autophagy, has been published in the journal PLoS One. The paper by Biskou et al., shows how intracellular organelle distribution can be altered by inhibitors of vimentin. This provides some key evidence as to how vimentin can actually regulate the process of autophagy, and has wide significance for a number of pathological conditions where autophagy is implicated.
Pubmed listing.
